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Endocrine Abstracts

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ea0094oc3.1 | Neuroendocrinology and Pituitary | SFEBES2023

CDC42: a potential therapeutic target of clinically non-functioning pituitary neuroendocrine tumours

Rai Ashutosh , Begalli Federica , Barry Sayka , Rice Thomas , Magid Kesson , Suleyman Oniz , Dorward Neil , Grieve Joan , Kolias Angelos , Khan Danyal , J Marcus Hani J. , Radotra Bishan D. , Chhabra Rajesh , Dhandapani S S. , Tripathi Manjul , Ahuja Chirag K. , Dutta Pinaki , Korbonits Marta

Background: There is no effective medical treatment available for non-functioning pituitary neuroendocrine tumours (NF-PitNETs). Recurrence (7-12%) or incomplete resection (30-45%) is a common feature. Thus, finding novel medical therapies to help the management of these tumours would be of great value. By using high-throughput mass spectrometry combined with functional characterisation, we explored novel therapeutic targets for NF-PitNETs.<p class="abstex...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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